منابع مشابه
Tolvaptan, hyponatremia, and heart failure
Tolvaptan is the first FDA-approved oral V(2) receptor antagonist for the treatment of euvolemic and hypervolemic hyponatremia, in patients with conditions associated with free water excess such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion. Tolvaptan inhibits the binding of arginine vasopressin to the V(2) receptors on the collecting ducts of the...
متن کاملHyponatremia in Acute Decompensated Heart Failure
Fro Ha ve Cle Gr fou rep Lis Yo Ma Hyponatremia frequently poses a therapeutic challenge in acute decompensated heart failure (ADHF). Treating physicians should differentiate between depletional versus dilutional hyponatremia. The former is caused by diuretic agents, which enhance sodium excretion, often with concomitant potassium/magnesium losses. This can be treated with isotonic saline, wher...
متن کاملSignificance of Hyponatremia in Heart Failure
Hyponatremia is a common clinical condition among hospitalized heart failure patients, associated with increased morbidity and mortality. The pathophysiological mechanisms that relate heart failure with hyponatremia are complex, involving beyond renal dysfunction, neurohormonal activation and diuretic treatment. The pituitary hormone vasopressin seems to play a central role leading to renal wat...
متن کاملHyponatremia in patients with heart failure.
Mild hyponatremia is encountered frequently in patients hospitalized for worsening heart failure. Admission plasma sodium concentration appears to be an independent predictor of increased mortality after discharge and rehospitalization. Recent studies have suggested that correction of hyponatremia may be associated with improved survival. This hypothesis is currently being studied in large pros...
متن کاملHyponatremia--risk factor in patients with chronic heart failure--clinical, evolutive and therapeutic implications.
UNLABELLED Patients with heart failure are, by definition, hemodynamically unstable. This condition may be accentuated by medication (digitalis, diuretics, antiarrhythmics), so that they become more sensitive to electrolyte disturbances. Hyponatremia is the most common electrolyte disorder, particularly common in the intensive care unit. AIM The evaluation of the incidence of hyponatremia in ...
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ژورنال
عنوان ژورنال: Cardiologia Croatica
سال: 2013
ISSN: 1848-543X,1848-5448
DOI: 10.15836/ccar.2013.444